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C4 is a network of computational chemists of the Swiss Federal Institute of Technology (ETH) Zürich, the external pageUniversity of Zürichcall_made and the external pageIBM Zürich Research Laboratory at Rüschlikoncall_made established in 1992. The purpose of C4 is to advance the frontiers in computation by carrying out research in the fields of chemistry, physics, biology and material science. C4 is led by a Steering Committee consisting of Markus Reiher (ETH Zürich; head), Jürg Hutter (University of Zürich), and Alessandro Curioni (IBM Zürich Research Laboratory).